Relationship between body mass index and mean arterial pressure in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study
نویسندگان
چکیده
BACKGROUND Being overweight is associated with both higher systolic blood pressure (SBP) and diastolic blood pressure (DBP) during pregnancy and increased risk of gestational hypertensive disorders. The objective of this study was to determine and quantify the effect of body mass index (BMI) on mean arterial pressure (MAP) at several time points throughout pregnancy in normotensive (NT) and chronic hypertensive pregnant (HT) women. METHODS A prospective longitudinal study was carried out in 461 singleton pregnancies (429 low-risk and 32 with chronic arterial hypertension), with measurements taken at the 1(st), 2(nd), and 3(rd) trimesters and at delivery. Linear mixed-effects regression models were used to evaluate the time-progression of BMI, SBP, DBP and MAP during pregnancy (NT vs. HT). The longitudinal effect of BMI on MAP, adjusted for the hypertensive status, was investigated by the same methodology. RESULTS BMI consistently increased with time in both NT and HT women. In contrast, MAP decreased during the first half of pregnancy, after which it increased until the moment of delivery in both groups. A 5-unit increase in BMI was predicted to produce an increase of approximately 1 mmHg in population MAP values. This effect is independent from the time period and from hypertensive status. CONCLUSIONS In both NT and HT pregnant women, MAP is strongly (and significantly) influenced by increases in BMI.
منابع مشابه
The effects of spinal anaesthesia for elective caesarean section on uterine and umbilical arterial pulsatility indexes in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study
BACKGROUND Despite the known effects of neuraxial blockade on major vessel function and the rapid decrease in uterine vascular impedance, it is unclear how the blockade affects the utero-placental circulation in the near-term. We hypothesize that among women with chronic hypertension, a loss of sympathetic tonus consequent to spinal block may cause significant changes in the utero-placental hae...
متن کاملPnm-15: The Effect of Maternal Body Mass Index on Preterm Birth in Women Referring to Health Centers of Ardebil in 2010: Prospective Study
Background: The aim of this study was to evaluate the relationship between prepregnancy maternal body mass Index (BMI) and preterm birth. Materials and Methods: This study included 231 healthy pregnant women, without any risk factors of preterm birth, were classified into categories that were based on their body mass index. Association between BMI, weight in 28-32 weeks of pregnancy, gestationa...
متن کاملارتباط فشارخون با شاخص توده بدن در سن 30- 18 سالگی در بین دانشجویان دانشگاه آزاد مهاباد
Abstract Background & Aim: High blood pressure is very important risk factor for cardiovascular disease but more symptoms of this disease are not evident in the adolescent period. This study aimed to investigate the relationship between blood pressure and mean arterial pressure, body mass index, as well as their prevalence at a younger age. Material & Method: This study is a descriptive c...
متن کاملAuthor's response to reviews Title:The effects of spinal anaesthesia for elective caesarean section on uterine and umbilical arterial pulsatility indexes in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study. Authors:
متن کامل
مقایسه میزان سرمی کلسیم کل و یونیزه در خانم‌های حامله مبتلا به پره‌اکلامپسی و خانم‌های با حاملگی طبیعی
The Comparison of Total and Ionised Serum Calcium Level in Preeclamptic Pregnant Women and the Women with Normal Pregnancy Z. Salari MD1*, N. Eftekhari MD2 1- Assistan Professor, Dept of Gynecology, University of Medical Sciences, Kerman, Iran 2- Associated Professor, Dept of Gynecology, University of Medical Sciences, Kerman, Iran Background: Preeclampsia remains one of the imp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2015